ActiClean Etox efficiently removes endotoxins from water, buffers, cell culture media, and protein solutions, including plasma proteins: Albumin, factor VIII, factor IX, IVIG with minimal non-specific binding. The immobilized ligand is non-toxic, and leaching is negligible. ActiClean Etox is easily regenerated for reuse. There is a Drug Master File available with the FDA. Incompatible with heavy metals and DNA.
| Bead Material | Agarose |
| Bead Percentage | 4% |
| Bead Size | 60-160 µm |
| Binding Capacity | >20,000 EU/mL |
| Flow Rate1 | >20 mL/min (>680 cm/hr) @ 25oC |
| pH Stability2 | 2-14 |
| Storage Temperature | 2-8o C |
| Storage Buffer | 20% Ethanol |
| Form | Slurry |
| Chemical Stability2 | 1M NaOH, 8M urea, 6M guanidine, ethanol, and common buffers. Incompatible with heavy metals and DNA. |
| Physical Stability2 | Negligible volume variation due to changes in pH or ionic strength. |
1. Linear flow rate = volumetric flow rate (cm3/h)/column cross-sectional area (cm2)
2. Data refer to the coupled product, provided that the ligand can withstand the pH or chemical environment. Please note the following: pH stability, long term refers to the pH interval where the medium is stable over a long period of time without adverse effects on its subsequent chromatographic performance. pH stability, short term refers to the pH interval for regeneration and cleaning procedures.